Pagoclone

Buy Pagoclone, Pagoclone is an anxiolytic drug from the cyclopyrrolone family that is related to other better-known drugs such as the sleep aid zopiclone. It belongs to a relatively newly developed class of drugs called non-benzodiazepines, which have similar effects to the older group of benzodiazepines but have a very different chemical structure

The synthesis of Pagoclone The synthesis of pagoclones involves the reaction of 2-amino-7-chloro-1,8-naphthyridine with phthalic anhydride, which leads to the corresponding phthalimide. A selective reduction of one of the imide carbonyl groups yields the corresponding alcohol

Pagoclone is a small molecular compound with the chemical formula C23H22ClN3O2. The average molecular weight is 407.893 g/mol.

research applications in science

Anti-anxiety properties: Pagoclone acts as a partial agonist at the γ-aminobutyric acid (GABA) A/benzodiazepine (BDZ) receptor and exhibits anti-anxiety properties without the typical side effects of benzodiazepines such as sedation and tolerance.

Neuropsychological performance: Studies show that higher doses may have mild adverse effects on learning and memory, although these changes are not statistically significant and disappear after six days of use.

Developmental Disorders: An exploratory study showed that Pagoclone effectively reduced stuttering symptoms.

Pharmacological effects: Research suggests that its anxiolytic effects are mediated by its primary metabolite 5′-hydroxypagoclone.

Pagoclone represents a potential advance in the treatment of anxiety and panic disorders. Its development includes phases of clinical trials that underline its potential as an effective treatment option.

Learn more about the anti-anxiety effects of Pagoclone (C23H22ClN3O2) and its use in anxiety disorders at NarcoChems.com.

Learn more about Pagoclone.